鮑氏不動桿菌為格蘭氏陰性，非葡萄糖發酵，成球狀或桿狀，為院內感染常見的細菌，可造成菌血症、肺炎、傷口感染、泌尿道感染等，一般對於常用抗生素皆抗藥，且可快速獲得新抗藥能力。其carbapenem抗藥率也逐年上升。偶有社區型感染，但多是在免疫有問題的宿主身上。
TSAR 研究成果：
1. Chen FJ, Huang WC, Liao YC, Wang HY, Lai JF, Kuo SC, Lauderdale TL, Sytwu HK. Molecular Epidemiology of Emerging Carbapenem Resistance in Acinetobacter nosocomialis and Acinetobacter pittii in Taiwan, 2010 to 2014. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e02007-18. doi: 10.1128/AAC.02007-18. PMID: 30670429; PMCID: PMC6496155.
2. Yang YS, Lee Y, Tseng KC, Huang WC, Chuang MF, Kuo SC, Lauderdale TL, Chen TL. In Vivo and In Vitro Efficacy of Minocycline-Based Combination Therapy for Minocycline-Resistant Acinetobacter baumannii. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4047-54. doi: 10.1128/AAC.02994-15. PMID: 27114274; PMCID: PMC4914616.
3. Chuang YC, Sheng WH, Lauderdale TL, Li SY, Wang JT, Chen YC, Chang SC. Molecular epidemiology, antimicrobial susceptibility and carbapenemase resistance determinants among Acinetobacter baumannii clinical isolates in Taiwan. J Microbiol Immunol Infect. 2014 Aug;47(4):324-32. doi: 10.1016/j.jmii.2013.03.008. Epub 2013 May 28. PMID: 23726465.
4. Kuo SC, Chang SC, Wang HY, Lai JF, Chen PC, Shiau YR, Huang IW, Lauderdale TL; TSAR Hospitals. Emergence of extensively drug-resistant Acinetobacter baumannii complex over 10 years: nationwide data from the Taiwan Surveillance of Antimicrobial Resistance (TSAR) program. BMC Infect Dis. 2012 Aug 28;12:200. doi: 10.1186/1471-2334-12-200. PMID: 22929085; PMCID: PMC3462144.