A. baumannii is a gram-negative, non-fermenting coccobacillus. It is one of the most prevalent pathogens causing healthcare-associated infections. It causes bloodstream infections, pneumonia, skin and soft tissue infections, and urinary tract infections. A. baumannii is intrinsic resistant to many antibiotics and acquires new resistance mechanism quickly. The carbapenem resistance rate has been increasing. A. baumannii sometimes causes community-acquired infections but almost all patients have underlying diseases.
TSAR Publications：
1. Chen FJ, Huang WC, Liao YC, Wang HY, Lai JF, Kuo SC, Lauderdale TL, Sytwu HK. Molecular Epidemiology of Emerging Carbapenem Resistance in Acinetobacter nosocomialis and Acinetobacter pittii in Taiwan, 2010 to 2014. Antimicrob Agents Chemother. 2019 Mar 27;63(4):e02007-18. doi: 10.1128/AAC.02007-18. PMID: 30670429; PMCID: PMC6496155.
2. Yang YS, Lee Y, Tseng KC, Huang WC, Chuang MF, Kuo SC, Lauderdale TL, Chen TL. In Vivo and In Vitro Efficacy of Minocycline-Based Combination Therapy for Minocycline-Resistant Acinetobacter baumannii. Antimicrob Agents Chemother. 2016 Jun 20;60(7):4047-54. doi: 10.1128/AAC.02994-15. PMID: 27114274; PMCID: PMC4914616.
3. Chuang YC, Sheng WH, Lauderdale TL, Li SY, Wang JT, Chen YC, Chang SC. Molecular epidemiology, antimicrobial susceptibility and carbapenemase resistance determinants among Acinetobacter baumannii clinical isolates in Taiwan. J Microbiol Immunol Infect. 2014 Aug;47(4):324-32. doi: 10.1016/j.jmii.2013.03.008. Epub 2013 May 28. PMID: 23726465.
4. Kuo SC, Chang SC, Wang HY, Lai JF, Chen PC, Shiau YR, Huang IW, Lauderdale TL; TSAR Hospitals. Emergence of extensively drug-resistant Acinetobacter baumannii complex over 10 years: nationwide data from the Taiwan Surveillance of Antimicrobial Resistance (TSAR) program. BMC Infect Dis. 2012 Aug 28;12:200. doi: 10.1186/1471-2334-12-200. PMID: 22929085; PMCID: PMC3462144.